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kraken2-taxonomic-classifier

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Kraken2 taxonomic classification skill for rapid metagenomic read assignment

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Source SKILL.md: https://github.com/a5c-ai/babysitter/blob/HEAD/library/specializations/domains/science/bioinformatics/skills/kraken2-taxonomic-classifier/SKILL.md

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Kraken2 Taxonomic Classifier Skill

Purpose

Provide Kraken2 taxonomic classification for rapid metagenomic read assignment.

Capabilities

  • k-mer based classification
  • Custom database creation
  • Confidence score filtering
  • Bracken abundance estimation
  • Multi-sample reporting
  • Memory-efficient operation

Usage Guidelines

  • Build or download appropriate databases
  • Set confidence thresholds for accuracy
  • Use Bracken for abundance estimation
  • Generate reports for visualization
  • Consider memory requirements
  • Document database versions

Dependencies

  • Kraken2
  • Bracken
  • Centrifuge

Process Integration

  • Shotgun Metagenomics Pipeline (shotgun-metagenomics)
  • 16S rRNA Microbiome Analysis (16s-microbiome-analysis)