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metaphlan-profiler

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MetaPhlAn metagenomic profiling skill for species-level community composition

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How to use this skill

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Source SKILL.md: https://github.com/a5c-ai/babysitter/blob/HEAD/library/specializations/domains/science/bioinformatics/skills/metaphlan-profiler/SKILL.md

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MetaPhlAn Profiler Skill

Purpose

Enable MetaPhlAn metagenomic profiling for species-level community composition.

Capabilities

  • Clade-specific marker gene analysis
  • Species-level quantification
  • Strain-level profiling (StrainPhlAn)
  • Unknown species estimation
  • Multi-sample heatmaps
  • Comparative analysis

Usage Guidelines

  • Use latest marker database
  • Profile at species level for most analyses
  • Apply strain-level analysis when relevant
  • Visualize community composition
  • Compare across samples and conditions
  • Document database versions

Dependencies

  • MetaPhlAn4
  • StrainPhlAn
  • mOTUs

Process Integration

  • Shotgun Metagenomics Pipeline (shotgun-metagenomics)