Esmfold2
Othersesmfold2Esmfold2 is an Agent Skill for general use published in the companion-inc/feynman repository on GitHub: a SKILL.md instruction file an AI agent can load to do this task.
Predict quick protein structures with ESMFold-style workflows. Use when a task needs fast MSA-free folding, sequence triage, variant structure screening, or confidence review.
QUICK START
How to use this skill
Bring this guide into your coding agent with a prompt tailored to the tool you use.
- Open your project in Codex.
- Copy and paste the prompt below.
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Prompt to paste
Inspect the Agent Skill at https://github.com/companion-inc/feynman/blob/HEAD/skills/esmfold2/SKILL.md and all supporting files. Report provenance, permissions, scripts, dependencies, and security risks. Propose an exact installation into .agents/skills/esmfold2, but wait for my approval before writing files or running scripts.
Copying this prompt does not install or run the skill. Review third-party files before use.
ESMFold2
Use this skill when a fast protein fold hypothesis is useful before heavier structure prediction.
Workflow:
- Normalize sequences into FASTA and record identifiers, mutations, truncations, domains, and oligomer assumptions.
- Verify the local or endpoint route before running.
- Save FASTA, model version, command or request body, predicted PDB/mmCIF, pLDDT/confidence outputs, and logs.
- Flag low-confidence regions, missing multimers, disorder, membrane regions, and sequence lengths outside the chosen route's limits.
- Use RDKit/3Dmol/PDB previews and source-backed comparisons when the output influences a research decision.
Use ESMFold-style predictions for triage unless an independent check supports the structural claim.