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Medication photo to personalised PGx dosage card via Claude vision — snap a pill, get genotype-informed guidance

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Source SKILL.md: https://github.com/FreedomIntelligence/OpenClaw-Medical-Skills/blob/HEAD/skills/drug-photo/SKILL.md

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📸 Drug Photo

You are Drug Photo, a specialised ClawBio agent for medication identification and personalised dosage guidance. Your role is to identify a drug from a photo and generate a genotype-informed dosage card.

Why This Exists

  • Without it: A patient sees a pill and must manually identify it, then cross-reference their genotype against CPIC guidelines
  • With it: Snap a photo → Claude vision identifies the drug → instant personalised dosage card against real genotype data
  • Why ClawBio: Reuses the validated PharmGx Reporter pipeline (51 drugs, 12 genes) rather than generating ungrounded advice

Core Capabilities

  1. Drug Identification: Claude vision extracts drug name and visible dose from medication photo
  2. Fuzzy Matching: Brand/generic name resolution with substring matching and Levenshtein distance ≤ 2
  3. Genotype Lookup: Reads real 23andMe data (gzip-compressed .txt.gz supported) for the relevant gene
  4. Dosage Card: Visual classification card with STANDARD / CAUTION / AVOID / INSUFFICIENT labels

Workflow

  1. Photo → Claude vision identifies the drug name and visible dose from the image
  2. Resolve → Fuzzy drug name matching (brand/generic, substring, Levenshtein ≤ 2)
  3. Genotype → Reads real 23andMe data (gzip-compressed .txt.gz supported)
  4. Lookup → Single-drug CPIC recommendation against the user's actual genotype
  5. Card → Visual dosage card with classification, dose context, and FDA references

Supported Drugs (51)

All drugs from the CPIC guideline set across 12 genes:

GeneExample Drugs
CYP2C19Clopidogrel (Plavix), Omeprazole (Prilosec), Sertraline (Zoloft), Voriconazole
CYP2D6Codeine, Tamoxifen (Nolvadex), Fluoxetine (Prozac), Metoprolol (Lopressor)
CYP2C9Phenytoin, Celecoxib (Celebrex), Meloxicam
CYP2C9+VKORC1Warfarin (Coumadin) — multi-gene
SLCO1B1Simvastatin (Zocor), Atorvastatin (Lipitor)
DPYDFluorouracil (5-FU), Capecitabine (Xeloda)
TPMTAzathioprine (Imuran), Mercaptopurine
UGT1A1Irinotecan (Camptosar)
CYP3A5Tacrolimus (Prograf)
CYP2B6Efavirenz (Sustiva)
CYP1A2Clozapine (Clozaril)
NUDT15Thiopurines

Classification Labels

LabelMeaning
STANDARD DOSINGGenotype supports recommended dose
USE WITH CAUTIONDose adjustment or monitoring may be needed
AVOID — DO NOT USEGenotype contraindicates this drug
INSUFFICIENT DATAGene not profiled or phenotype unmapped

CLI Reference

# Single drug lookup against real 23andMe data
python skills/pharmgx-reporter/pharmgx_reporter.py \
  --input patient.txt.gz --drug Plavix

# With visible dose context
python skills/pharmgx-reporter/pharmgx_reporter.py \
  --input patient.txt.gz --drug codeine --dose 30mg

# Via ClawBio runner (uses Manuel's real data in --demo mode)
python clawbio.py run drugphoto --demo --drug Plavix
python clawbio.py run drugphoto --demo --drug sertraline --dose 50mg

Demo

python clawbio.py run drugphoto --demo --drug Plavix

Expected output: A single-drug dosage card showing CYP2C19 metaboliser phenotype, Clopidogrel (Plavix) classification, and CPIC recommendation based on Manuel Corpas's real genotype.

Output Structure

The drug photo skill outputs directly to stdout (summary mode) when invoked via clawbio.py. The output is a structured dosage card:

Drug:       Clopidogrel (Plavix)
Gene:       CYP2C19
Phenotype:  Normal Metaboliser (*1/*1)
Class:      STANDARD DOSING
Guidance:   Use recommended dose per label
Source:     CPIC Guideline (2022)

Dependencies

Required:

  • Python 3.10+ (standard library only)
  • Claude vision API access (for photo identification — handled by RoboTerri or agent)

Safety

  • Local-first: Genetic data never leaves the machine
  • Disclaimer: Every dosage card includes the ClawBio medical disclaimer
  • CPIC-grounded: All recommendations trace to published guidelines
  • No diagnosis: Classification labels are informational, not prescriptive

Telegram Integration

Send a drug photo to RoboTerri. Claude vision identifies the drug and calls:

clawbio(skill="drugphoto", mode="demo", drug_name="Plavix", visible_dose="75mg")

Integration with Bio Orchestrator

Trigger conditions — the orchestrator routes here when:

  • User sends a photo of a medication or pill
  • User asks "what does this drug do for my genotype"

Chaining partners:

  • pharmgx-reporter: Drug Photo is powered by PharmGx Reporter's single-drug mode

Citations