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python-deploy

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Build and deploy Python applications — uv, poetry, pdm, pipenv, pip, framework detection, and Dockerfile patterns. Use when deploying a Python project, or when requirements.txt, pyproject.toml, or Pipfile is detected.

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Python Deployment

Detection

Project is Python if any of these exist:

FilePackage manager / style
pyproject.tomlModern (PEP 517/518), uv, poetry, pdm, or pip
requirements.txtpip
setup.pysetuptools
PipfilePipenv

Entry point files (checked in order): app.py, main.py, server.py, run.py, wsgi.py, asgi.py

Versions

Python version priority:

  1. .python-version file or mise.toml / .tool-versions
  2. pyproject.toml → [project].requires-python (e.g. >=3.11)
  3. Pipfile → [requires].python_version
  4. runtime.txt
  5. Defaults to 3.13

Package Managers

Detect in order:

  1. Lock files: poetry.lock → Poetry, pdm.lock → PDM, Pipfile.lock → Pipenv, uv.lock → uv
  2. Manifest: pyproject.toml (poetry/pdm/uv) or Pipfile (pipenv) or requirements.txt (pip)
  3. Default: pip with requirements.txt

Install Commands

ManagerInstall command
pippip install --no-cache-dir -r requirements.txt
Poetrypoetry install --only main --no-interaction
PDMpdm install --prod --no-lock
uvuv sync --frozen --no-dev
Pipenvpipenv install --deploy --system

Runtime Variables

Configure the Python runtime for production: enable the fault handler for crash diagnostics (PYTHONFAULTHANDLER=1), disable output buffering for real-time logs (PYTHONUNBUFFERED=1), randomize hash seeds (PYTHONHASHSEED=random), and skip bytecode generation (PYTHONDONTWRITEBYTECODE=1). Suppress pip version checks with PIP_DISABLE_PIP_VERSION_CHECK=1.

Build & Start

Start Command Resolution

  1. Framework-specific (see below)
  2. pyproject.toml → [project.scripts] or [tool.poetry.scripts]
  3. setup.py → entry_points
  4. manage.py → Django
  5. Root entry files (first found): app.py, main.py, server.py, run.py → python <file>
  6. Conventions: wsgi.py, asgi.py

Most Python web apps have no build step (interpreted).

Port Detection

  1. PORT from .env or .env.example
  2. Framework defaults:
FrameworkDefault port
Flask5000
Django / FastAPI / Starlette / Gunicorn / Uvicorn8000
Streamlit8501
Gradio7860
Default8000

Framework Detection

From dependencies in pyproject.toml, requirements.txt, or Pipfile:

Package patternFrameworkCategory
flaskFlaskBackend
djangoDjangoFullStack
fastapiFastAPIBackend
starletteStarletteBackend
python-fasthtmlFastHTMLBackend
uvicornASGI serverBackend
gunicornWSGI serverBackend
streamlitStreamlitApp
gradioGradioApp
pelicanPelicanStatic
mkdocsMkDocsDocs

Framework-Specific Start Commands

Flask — gunicorn <module>:app -b 0.0.0.0:${PORT:-5000} if gunicorn is a dependency, else flask run Django — python manage.py migrate && gunicorn <wsgi_module>:application -b 0.0.0.0:${PORT:-8000} --workers 2. Detect app from WSGI_APPLICATION in settings. FastAPI — uvicorn <module>:app --host 0.0.0.0 --port ${PORT:-8000} --workers 1 FastHTML — uvicorn <module>:app --host 0.0.0.0 --port ${PORT:-8000} Streamlit — streamlit run <entry>.py --server.port ${PORT:-8501} --server.address 0.0.0.0

System Dependencies

PackageBuild-timeRuntime
psycopg2libpq-dev, gcclibpq5
mysqlclientdefault-libmysqlclient-dev, gcclibmariadb3
pillowlibjpeg-dev, zlib1g-dev, libfreetype6-dev—
cryptographylibssl-dev, libffi-dev—
pycairolibcairo2-dev, pkg-configlibcairo2
lxmllibxml2-dev, libxslt1-devlibxml2, libxslt1.1
pycurllibcurl4-openssl-dev—
pdf2image—poppler-utils
pydub—ffmpeg
playwright—Chromium headless shell

Install Stage Optimization

Copy pyproject.toml + lockfile first for layer caching, then full source.

Caching

Leverage BuildKit cache mounts to speed up rebuilds:

  • pip: RUN --mount=type=cache,target=/root/.cache/pip pip install -r requirements.txt
  • uv: RUN --mount=type=cache,target=/root/.cache/uv uv sync --frozen

Environment Variable Semantics

PatternLikely dependency
DATABASE_URLPostgreSQL, MySQL
REDIS_URLRedis
SECRET_KEYDjango, Flask
DJANGO_SETTINGS_MODULEDjango
AWS_* / S3_*AWS

Dockerfile Patterns

uv (with lockfile)

FROM python:3.13-slim AS base

FROM base AS deps
WORKDIR /app
COPY pyproject.toml uv.lock ./
RUN pip install uv && uv sync --frozen

FROM base AS runtime
WORKDIR /app
ENV PYTHONUNBUFFERED=1 PYTHONDONTWRITEBYTECODE=1
COPY --from=deps /app/.venv /app/.venv
ENV PATH="/app/.venv/bin:$PATH"
COPY . .
EXPOSE 8000
CMD ["uvicorn", "main:app", "--host", "0.0.0.0", "--port", "8000"]

pip + requirements.txt

FROM python:3.13-slim AS base

FROM base AS deps
WORKDIR /app
COPY requirements.txt ./
RUN pip install --no-cache-dir -r requirements.txt

FROM base AS runtime
WORKDIR /app
ENV PYTHONUNBUFFERED=1 PYTHONDONTWRITEBYTECODE=1
COPY --from=deps /usr/local/lib/python3.13/site-packages /usr/local/lib/python3.13/site-packages
COPY . .
EXPOSE 8000
CMD ["gunicorn", "wsgi:app", "-b", "0.0.0.0:8000"]

Django with collectstatic

FROM python:3.13-slim AS base

FROM base AS deps
WORKDIR /app
COPY requirements.txt ./
RUN pip install --no-cache-dir -r requirements.txt

FROM base AS build
WORKDIR /app
COPY --from=deps /usr/local/lib/python3.13/site-packages /usr/local/lib/python3.13/site-packages
COPY . .
ENV DJANGO_SETTINGS_MODULE=project.settings
RUN python manage.py collectstatic --noinput

FROM base AS runtime
WORKDIR /app
ENV PYTHONUNBUFFERED=1 PYTHONDONTWRITEBYTECODE=1
COPY --from=build /usr/local/lib/python3.13/site-packages /usr/local/lib/python3.13/site-packages
COPY --from=build /app/static /app/static
COPY --from=build /app /app
EXPOSE 8000
CMD ["gunicorn", "project.wsgi:application", "-b", "0.0.0.0:8000"]

Gotchas

  • psycopg2 requires libpq-dev and gcc at build time — use psycopg2-binary instead to avoid native compilation
  • uv --frozen fails if uv.lock doesn't exist — use uv sync without --frozen when no lockfile is present
  • Django collectstatic needs DJANGO_SETTINGS_MODULE and may require a dummy SECRET_KEY at build time
  • Poetry creates virtual environments outside the project by default — set POETRY_VIRTUALENVS_IN_PROJECT=true for Docker builds
  • FastAPI/Uvicorn must bind to 0.0.0.0, not 127.0.0.1, to be reachable from outside the container
  • Python site-packages path includes the minor version (e.g. python3.13) — the COPY path in multi-stage Dockerfiles must match the exact Python version