target-drug-report

Business

Generate comprehensive drug development progress reports for disease therapeutic targets. Use when user asks about target drug pipeline, clinical trials, or research progress. Triggers on phrases like "target report", "drug development progress", "clinical trial summary", "靶点报告", "药物研发进展", "竞品分析", "专利分析".

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Target Drug Development Report (Enhanced)

Overview

Generate beautiful, comprehensive reports on drug development progress for therapeutic targets.

Features:

7 analysis sections with visualizations
HTML and Markdown output formats
Responsive design for all devices
Print-friendly for PDF export

When to Use

User asks about a specific target's drug development status
Need to summarize clinical trial progress for a target
Researching competitive landscape for a therapeutic target
Understanding drug pipeline and market opportunities

Workflow

from open_biomed.tools.tool_registry import TOOLS

target_name = "CGRP"

# Step 1: Multi-source search
web_search = TOOLS["web_search"]

# Search clinical trials
trial_results, _ = web_search.run(
    query=f"{target_name} clinical trial 2024 2025"
)

# Search research papers
paper_results, _ = web_search.run(
    query=f"{target_name} discovery mechanism site:pubmed.ncbi.nlm.nih.gov"
)

# Step 2: Generate report
report = generate_target_report(
    target=target_name,
    output_format="html"  # or "markdown"
)

Report Sections

Section	Description	Key Content
🎯 靶点概况	Target overview	Protein function, diseases
💊 已上市药物	Approved drugs	Name, company, indication
🏥 临床管线	Clinical pipeline	Phase distribution, drugs
📚 研究热点	Research trends	Publications, directions
📜 专利布局	Patent landscape	Trends, applicants
📊 市场分析	Market analysis	Size, competition
🔮 投资展望	Investment outlook	Opportunities, risks

Output Formats

HTML (推荐)

Modern responsive design
Interactive charts and progress bars
Color-coded status tags
Print to PDF support

Markdown

Plain text format
Table-based layout
Version control friendly
Easy to edit

Usage

# Generate HTML report
report = generate_target_report("EGFR", output_format="html")

# Generate Markdown report
report = generate_target_report("KRAS", output_format="markdown")

# Save to file
report = generate_target_report(
    target="BCL-2",
    output_format="html",
    output_path="report.html"
)

Error Handling

When web search is unavailable, uses built-in knowledge for common targets:

EGFR, KRAS, BCL-2, ALK, BRAF, HER2 (Oncology)
PD-1, CTLA-4 (Immunology)
CGRP, JAK, BTK (Other)

Files

target-drug-report/
├── SKILL.md                    # This file
├── examples/
│   └── basic_example.py        # Report generator script
└── references/
    ├── html_template.py        # HTML template
    └── data_sources.md         # Data source reference

Limitations

Requires network for real-time data
Built-in knowledge for ~20 common targets
Patent data may be incomplete