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ginkgo-cloud-lab

Apps & Automation
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Submit and manage protocols on Ginkgo Bioworks Cloud Lab (cloud.ginkgo.bio), a web-based interface for autonomous lab execution on Reconfigurable Automation Carts (RACs). Use when the user wants to run cell-free protein expression (validation or optimization), generate fluorescent pixel art, or interact with Ginkgo Cloud Lab services. Covers protocol selection, input preparation, pricing, and ordering workflows.

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How to use this skill

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Source SKILL.md: https://github.com/mkurman/zorai/blob/HEAD/skills/scientific-skills/ginkgo-cloud-lab/SKILL.md

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Ginkgo Cloud Lab

Overview

Ginkgo Cloud Lab (https://cloud.ginkgo.bio) provides remote access to Ginkgo Bioworks' autonomous lab infrastructure. Protocols are executed on Reconfigurable Automation Carts (RACs) -- modular units with robotic arms, maglev sample transport, and industrial-grade software spanning 70+ instruments.

The platform also includes EstiMate, an AI agent that accepts human-language protocol descriptions and returns feasibility assessments and pricing for custom workflows beyond the listed protocols.

Available Protocols

1. Cell Free Protein Expression Validation

Rapid go/no-go expression screening using reconstituted E. coli CFPS. Submit a FASTA sequence (up to 1800 bp) and receive expression confirmation, baseline titer (mg/L), and initial purity with virtual gel images.

2. Cell Free Protein Expression Optimization

DoE-based optimization across up to 24 conditions per protein (lysates, temperatures, chaperones, disulfide enhancers, cofactors). Designed for difficult-to-express and membrane proteins.

3. Fluorescent Pixel Art Generation

Transform a pixel art image (48x48 to 96x96 px, PNG/SVG) into fluorescent bacterial artwork using up to 11 E. coli strains via acoustic dispensing. Delivered as high-res UV photographs.

General Ordering Workflow

  1. Select a protocol at https://cloud.ginkgo.bio/protocols
  2. Configure parameters (number of samples/proteins, replicates, plates)
  3. Upload input files (FASTA for protein protocols, PNG/SVG for pixel art)
  4. Add any special requirements in the Additional Details field
  5. Submit and receive a feasibility report and price quote

For protocols not listed above, use the EstiMate chat to describe a custom protocol in plain language and receive compatibility assessment and pricing.

Authentication

Access Ginkgo Cloud Lab at https://cloud.ginkgo.bio. Account creation or institutional access may be required. Contact Ginkgo at cloud@ginkgo.bio for access questions.

Key Infrastructure

  • RACs (Reconfigurable Automation Carts): Modular robotic units with high-precision arms and maglev transport
  • Catalyst Software: Protocol orchestration, scheduling, parameterization, and real-time monitoring
  • 70+ integrated instruments: Sample prep, liquid handling, analytical readouts, storage, incubation
  • Nebula: Ginkgo's autonomous lab facility in Boston, MA